IndraLab

Statements


USP37 deubiquitinates Cyclin. 4 / 4
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"USP37 deubiquitinates and stabilizes Cyclin A and promotes S phase entry."

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"Usp37 binds APC/C Cdh1 in G1 and deubiquitinates the APC/C substrate cyclin A [XREF_BIBR]."

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"Deubiquitination and stabilization of the APC/C substrate cyclin A by USP37 enables entry into S phase."

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"These results argue that USP37 deubiquitinates cyclin A directly as opposed to being an EMI1-type APC/C inhibitor."