IndraLab

Statements

Resveratrol inhibits CASP1. 6 / 9
3 | 6
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"Resveratrol and regular exercise significantly decreased nlrp3 mRNA and protein expression, the ratio of cleaved-caspase-1/pro-caspase-1 and mature-IL-1β/pro-IL-1β in the hypertensive group."
35196531
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"Recently, a study revealed that resveratrol therapy efficiently reduced the maturation of caspase-1 and IL-1β in response to TLR1/2 agonist Pam3CSK4 as well as NLRP3-inflammasome inducers such as nigericin, silica, ATP, and MSU [214]."
36006570
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"Interestingly, in this last report, resveratrol was also shown to reduce the expression of the NLRP3 inflammasome players ASC and Caspase-1."
35637440
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"Resveratrol pretreatment also inhibited the activation of NLRP3 and caspase-1, and reduced the production of inflammatory cytokines and ROS."
29257276
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"Resveratrol (100muM) treatment reduced caspase-1 immunofluorescence intensity compared with ox-LDL-treated platelets."
33728029
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"In a recent study [XREF_BIBR], it was found that resveratrol treatment successfully suppressed the maturation of both IL-1beta and caspase-1 in response to Pam3CSK4; a TLR1/2 agonist, plus various inducers (like nigericin, ATP, MSU, and silica) of the NLRP3-inflammasome."
27672241