IndraLab

Statements

KCNH2 activates ion channel. 3 / 3
| 3
reach
"Fluoxetine is a compound with hERG channel blocking effects 28 as well as other off target ion channel block, including : Nav1.5 29, and voltage gated calcium channels 30."
29061979
reach
"Mutations in the KCNH2 gene were reported to cause type 2 long QT syndrome (LQT2), a rare inherited ion channel disorder characterized by prolonged QT interval and predisposing patients to ventricular arrhythmias that can lead to syncope and sudden cardiac death (SCD)."
27064559
reach
"Similar action potential prolongation was seen in these experiments with astemizole and hiPSC-CM.To summarize, in the present study, all hERG blockers prolonged action potential duration in hiPSC–CM a[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
25219538