IndraLab

Statements


2 | 4

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sparser
"To solve this question, we will investigate whether this lncRNA affects the interaction of USP47 with RPL11 or the deubiquitination and translocation of RPL11 by USP47, and thus is involved in the p53 protein levels as in our models."

sparser
"To confirm this possibility, we first investigated the interaction between USP47 and RPL11."

sparser
"When we co-transfected with Flag-tagged USP47 and HA-tagged RPL11 in the cells, and we observed the binding of USP47 to RPL11 by immunoprecipitation with anti-Flag magnetic beads ( xref a)."

sparser
"In addition, USP47 binds to and deubiquitinates RPL11, and USP47-induced RPL11 deubiquitination is inhibited by miR-101-3p."