IndraLab

Statements


OTUD7B activates MTOR. 3 / 3
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"Overall, our results suggest that OTUD7B knockdown reduces autophagy by activating AKT/mTOR signaling in PC3 cells."

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"To identify the underlying mechanism, we speculated that OTUD7B knockdown inhibits autophagy via the AKT/mTOR signaling pathway in PCa cells."

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"We found that Cezanne overexpression in NRCMs activated AKT/mTOR to reduce apoptosis, autophagy and oxidative stress; this mechanism of Cezanne was also verified in animal experiments."