IndraLab

Statements

CREB binds KCNA5. 4 / 4
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"3.3 Chromatin Immunoprecipitation shows that CREB binds to the Kv1.5 promoter in the heart."
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"Although this early work was suggestive, we have gone further by showing that CREB transfection increases the transcription of human and mouse Kv1.5 promoter reporter constructs, and that ChIP demonstrates binding of CREB to the Kv1.5 promoter in mouse heart."
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sparser
"To determine if CREB binds to the Kv1.5 promoter in the heart, mouse ventricular tissue was homogenized and chromatin immunoprecipitation (ChIP) was performed with an anti-CREB antibody."
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sparser
"We found that CREB knock-down by siRNA reduces Kv1.5, CREB binds to the Kv1.5 promoter in the heart, and CREB increases transcription of mouse and human Kv1.5 promoters."
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