IndraLab

Statements

ATP inhibits KCNMA1. 6 / 6
| 6
reach
"Although such features would be compatible with the presence of a K ATP channel in the RER, recent data obtained from a brain mitochondrial inner membrane preparation have provided evidence for a Maxi-K channel which could also be blocked by ATP within the mM concentration range."
25950903
reach
"In addition, our previous experiment showed that ATP inhibited brain mitochondrial BK channel activity [XREF_BIBR]."
24842143
reach
"The mB2 BK channel alpha-subunit variant expressed alone was potently inhibited by application of ATP to the intracellular surface of the patch with an IC50 of 30 microM."
10066921
reach
"As to the impact of ATP on BK channels it has been reported that ATP per see can inhibit BK channel activity."
25429270
reach
"These results suggest that besides the common natures of the BK channel family such as regulation by cytoplasmic Ca (2+) and membrane potential, the BK channel in RPTECs is directly inhibited by intracellular ATP independent of phosphorylation processes and sulfonylurea receptor."
11564285
reach
"In suprachiasmatic neurons, ATP decreases the open probability of a 260 pS BK channel at both negative and positive membrane potentials XREF_BIBR."
23284908