IndraLab

Statements


COPS5 bound to TGFB activates transcription, DNA-templated. 1 / 1
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reach
"Jab1 and COPS5 directly binds to Smad4 and degrades it through the proteasome pathway and thus attenuate TGF-beta mediated gene transcription, whereas its degradation of Smad7 results in enhanced TGF-beta signaling effects."