IndraLab

Statements

CircMED27 increases the amount of USP28. 3 / 3
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reach
"22 In this study, we concluded that circMED27 induces the lenvatinib resistance of HCC by upregulating the expression of USP28 and sponging miR-655-3p.In summary, we demonstrate that, for the first time, a circMED27 was upregulated in HCC serum and tissues."
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reach
"More importantly, circMED27 upregulated ubiquitin-specific peptidase 28 expression to revert LVN’s resistance via sponging miR-655-3p."
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reach
"Our mechanistic investigations revealed that circMED27 functions as a competing endogenous RNA (ceRNA) for miR-655-3p to upregulate ubiquitin-specific peptidase 28 (USP28) expression."
35024242