IndraLab

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UCHL1 activates CDKN2A. 1 / 1
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"The exact mechanism by which UCHL1 regulates tumor development remains uncertain, although recent data suggest that UCHL1 increases the half-life of p53 and p14 ARF, decreases the half-life of Mdm2, and activates the p53 signaling pathway XREF_BIBR, XREF_BIBR."