IndraLab

Statements

Toxin inhibits KCNB1. 2 / 2
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"The toxin inhibits DRK1 by binding to its S3-S4 linker and thereby hindering the movement of its gating charges."
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"In fact, the magnitude of NULL currents is comparable to that of WT (or R312H) currents in the presence of GxTx, indicating that the toxin primarily blocks Kcnb1 channels."
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