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USP22 increases the amount of TERF1. 2 / 3

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"Depletion of USP22 decreases TRF1 protein levels whereas overexpression of wild-type USP22 increases TRF1 levels in a manner dependent upon its enzymatic activity ( Atanassov et al., 2009 )."

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"Depleting USP22 decreases TRF1 levels and enhances cell death by genotoxic insults ."

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IndraLab

Statements

USP22 increases the amount of TERF1. 2 / 3

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