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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

ADIPOQ activates TNFAIP3. 2 / 2

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"Adiponectin can augment the expression of A20 rapidly and observably by stimulating glucose synthase kinase 3beta ( GSK3beta ) activity , resulting in macrophage quiescence and initiating an A20-mediated anti-inflammatory program [ 65 ] ."

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"A systematic search for adiponectin inducible genes with established anti-inflammatory properties revealed that adiponectin augmented the expression of A20, suppressor of cytokine signaling (SOCS) 3, B-cell CLL and lymphoma (BCL) 3, TNF receptor associated factor (TRAF) 1, and TNFAIP3 interacting protein (TNIP) 3."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...