IndraLab

Statements

USP7 deubiquitinates PRC1. 5 / 6
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"Lastly, USP7 and USP11 deubiquitinate PRC1, a protein found to contribute to cancer stemness [XREF_BIBR - XREF_BIBR]."
30831436
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"USP7 also deubiquitinates PRC1 and regulates LSD1/KDM1A, which has a role in embryonic development [35] ."
29864528
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"In certain cancer types, PRC1 has been found to be deubiquitinated by USP7 and USP11 ( Lecona, Narendra, & Reinberg, 2015; Maertens, Messaoudi-Aubert, Elderkin, Hiom, & Peters, 2010 )."
27919796
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"In some cancer types, PRC1 can be deubiquitinated by USP7, USP11 and USP26 [XREF_BIBR, XREF_BIBR]."
29142505
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"USP7 deubiquitinates several PRC1 subunits, and the inhibition of its activity results in destabilization of PRC1s and impaired silencing of Polycomb target genes."
37014752