IndraLab

Statements


Modified UCHL1 decreases the amount of PHLPP1. 1 / 1
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reach
"Exploring the underlying mechanism, we found that aberrant UCH-L1 expression leads to a dramatic increase in Akt signaling in vitro and in vivo by decreasing the levels of PHLPP1 : a phosphatase that reverses Akt phosphorylation."