IndraLab

Statements

Forskolin inhibits NLRP3. 7 / 7
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"Also, it has been reported that forskolin could attenuate the activation of NLRP3 inflammasome in human macrophages."
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"Forskolin attenuates the NLRP3 inflammasome activation and IL-1beta secretion in human macrophages."
31086288
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"Forskolin attenuates the NLRP3 inflammasome activation and IL-1beta secretion in human macrophages."
31434103
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"We first made sure that the BOT-4-one action would not be influenced by PKA activation by observing that the PKA inhibitor H-89 could not prevent the BOT-4-one-mediated inhibition of NLRP3 inflammasome activation, whereas it restored the NLRP3 inflammasome functionality (maturation of IL-1beta and caspase-1) suppressed by the adenylyl cyclase activator forskolin."
29118366
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"Forskolin treatment significantly decreased NLRP3 activation (XREF_FIG) and IL-1beta secretion (XREF_FIG), which was further decreased by adding PGE 2, suggesting additive PGE 2 -mediated mechanisms of adenylate cyclase activation."
25917098
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"Since forskolin can reduce NLRP3 inflammasome proteins (Liu et al, 2021, in submission), we wanted to measure P2X7R after forskolin treatment."
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"Forskolin inhibits the NLRP3 inflammasome activation and the secretion of mature IL-1beta, in human macrophages."
31086288