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UCHL1 inhibits HSPA5. 2 / 2

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"Knockdown of UCHL1 upregulated GRP78 in CFs with TGF-beta1 stimulation and inhibition of GRP78 diminished the antifibrotic effect of UCHL1 knockdown."

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"Moreover, we wondered if the effect of UCHL1 on fibrosis was related to GRP78, so we determined the GRP78 protein levels in CFs with and without TGF-beta1 and treated with and without UCHL1 knockdown."

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IndraLab

Statements

UCHL1 inhibits HSPA5. 2 / 2

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