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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

UCHL1 inhibits HSPA5. 2 / 2

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"Knockdown of UCHL1 upregulated GRP78 in CFs with TGF-beta1 stimulation and inhibition of GRP78 diminished the antifibrotic effect of UCHL1 knockdown."

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"Moreover, we wondered if the effect of UCHL1 on fibrosis was related to GRP78, so we determined the GRP78 protein levels in CFs with and without TGF-beta1 and treated with and without UCHL1 knockdown."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...