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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

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INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

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SCN5A increases the amount of MEF2C. 4 / 4

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"HuR upregulates MEF2C mRNA expression by protecting MEF2C mRNA from degradation, and consequently, the elevated MEF2C enhances SCN5A mRNA transcription."

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"MEF2C Enhances SCN5A Transcription."

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"We then tested if the association of MEF2C and the SCN5A gene regulated SCN5A transcription."

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"As demonstrated by both chromatin immunoprecipitation-quantitative polymerase chain reaction assay and an electrophoretic mobility shift assay, MEF2C enhanced SCN5A transcription by binding to a putative MEF2C binding site within SCN5A promoter region."

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INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...

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SCN5A increases the amount of MEF2C. 4 / 4

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