IndraLab

Statements

USP3 deubiquitinates Histone_H2B. 7 / 7
| 7
reach
"Exogenous USP3 deubiquitinates H2A and H2B ( Nicassio et al., 2007 ) and overexpression of USP16 and USP44 reverses RNF8/RNF168-mediated ubiquitination ( Mosbech et al., 2013; Shanbhag et al., 2010 )."
24704006
reach
"USP3 that was found as chromatin associated DUB suppresses global mono-ubiquitylation of H2A (and also H2B)."
28764946
reach
"Deubiquitination of histones H2A and H2B by USP3 is required for progression through the S phase and for genomic stability."
22941662
reach
"The involvement of USP3 in DDR was first reported in 2007 by Nicassio et al. 32 According to their findings, USP3 is essential for the complete deubiquitylation of uH2A/H2B and γ‐H2AX through its enzymatic catalytic activity."
38651282
reach
"Usp3 can deubiquitinate both H2A and H2B in humans."
19489724
reach
"In addition to USP22 and its yeast homolog, H2B can be deubiquitylated by USP3 and USP7 in humans."
21513801
reach
"In the DDR, USP3 dynamically interacts with chromatin and deubiquitinates H2A and H2B."
26882840