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USP19 activates EWSR1-FLI1. 1 / 1
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eidos
"Depletion of USP19 was shown to decrease EWSR1-FLI1 expression levels , but neither the expression of wild-type of EWSR1 nor FLI1 , and to reduce tumor growth in vitro and in vivo indicating a potential therapeutic value for USP19 inhibition [ 101 ] ."