IndraLab

Statements

USP37 deubiquitinates Snail1. 5 / 5
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"Although PLAGL2 does not function as a deubiquitinase to impede Snail1 ubiquitination, PLAGL2 transcriptionally activates USP37, which finally interacts with and deubiquitinates Snail1 directly."
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"USP37 interacts with and deubiquitinates Snail1 directly."
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"Among these three DUBs, only USP37 significantly diminished the ubiquitination of Snail1, suggesting that USP37 may be a potential deubiquitinase of Snail1."
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"Overall, these results demonstrate that USP37 interacts with and deubiquitinates Snail1 directly."
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"We also determined that USP37 interacts with and deubiquitinates Snail1 directly, which is transcriptionally activated by PLAGL2."
33391500