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USP21 phosphorylated on S538 is active. 1 / 1

1 |

"In this study, we found that USP21 is an important deubiquitinating enzyme for STING and that it negatively regulates the DNA virus-induced production of type I interferons by hydrolyzing K27/63-linked polyubiquitin chain on STING. HSV-1 infection recruited USP21 to STING at late stage by p38-mediated phosphorylation of USP21 at Ser538. I"

28254948

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IndraLab

Statements

USP21 phosphorylated on S538 is active. 1 / 1

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