Other Services

This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

Modified OTUD1 increases the amount of SMURF1. 4 / 4

| 4

➶

reach

"RNA virus infection promotes NF-kappaB-dependent expression of OTUD1 that upregulates Smurf1 protein levels."

29734366

➶

reach

"In this study, we reveal that RNA virus infection activates expression of OTUD1, which in turn interacts with Smurf1 and upregulates Smurf1 protein levels by deubiquitination effects."

29734366

➶

reach

"We further found that OTUD1 overexpression upregulated protein level of Smurf1, rather than Smurf2 (XREF_SUPPLEMENTARY)."

29734366

➶

reach

"Overexpression of OTUD1 upregulated exogenous Smurf1 protein levels in a dose dependent manner (XREF_FIG)."

29734366

Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...

Other Services

This Service

This Project

IndraLab

Statements

Modified OTUD1 increases the amount of SMURF1. 4 / 4

Our Sources:

Databases

Reading