IndraLab

Statements

ID1 activates USP1. 3 / 3
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"Collectively, these data suggest that ID protein stabilization by USP1 in osteosarcoma blocks a normal osteogenic differentiation program.The potential of USP1 inhibition as a tumor differentiation st[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"Significantly, CDKN1A siRNAs restored S phase entry in USP1 deficient U2-OS cells, indicating that p21 is essential for the cell-cycle arrest induced by USP1 knockdown.If ID degradation in the absence[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"Importantly, ID1 is downstream target of USP1 31."
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