IndraLab

Statements

OTUB1 deubiquitinates SMAD2. 3 / 3
1 | 2
ubibrowser
"OTUB1 enhances TGFbeta signalling by inhibiting the ubiquitylation and degradation of active SMAD2/3."
24071738
reach
"OTUB1 could not directly de-ubiquitinate Smad2 and Smad3, while its effect is dependent on regulating ubiquitin E2 conjugating-enzyme activity."
27604640
reach
"Recently, OTUB1, a DUB, was reported to reduce poly-ubiquitination of Smad2 and Smad3 through inhibition of the E2 ubiquitin conjugating enzymes."
27604640