IndraLab

Statements

OTUB1 binds tumor necrosis factor receptor. 4 / 4
| 4
reach
"Through immunoprecipitation-mass spectrometry (IP-MS) analysis, we further found that OTUB1 directly bound to tumor necrosis factor receptor-associated factor 6 (TRAF6) and suppressed its lysine 63 (K63)-linked polyubiquitination, thus inhibiting the activation of ASK1 and its downstream pathway."
34591986
reach
"As the founding member of deubiquitinase, OTUB1 directly binds to tumor necrosis factor receptor-associated factor 6 (TRAF6) and blocks its ubiquitination, so as to suppress NASH/MASH through attenuat[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
38122854
reach
"The deubiquitinating enzyme ubiquitin aldehyde binding 1 (OTUB1) directly binds to tumor necrosis factor receptor-associated factor 6 (TRAF6) and inhibits its lysine 63-linked polyubiquitination, thereby inhibiting the activation of ASK1 and its downstream MAPK pathway 73.The ubiquitin system also plays an important role in the activation of other pathways."
39113708
reach
"OTUB1 can directly bind tumor necrosis factor receptor-associated factor 6 (TRAF6), inhibit its lysine 63-linked polyubiquitination, and thus inhibit the activation of apoptotic signal-regulated kinas[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
38219809