IndraLab

Statements

Mangiferin inhibits RELA. 4 / 4
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"Mangiferin treatment markedly reduced the NF-kappaB p65 activation in the colon."
25194678
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"Additionally, mangiferin prevented the STAT3 as well as NF-kappaBp65 signaling pathway activation in the cytosol, which resulted in the anti-inflammatory cytokines being upregulated, whereas, the pro inflammatory cytokines were downregulated."
33389907
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"Mangiferin significantly reduced the nuclear penetration of NF-kappaB p65, however, there were no changes in the expression of other survival signals, such as extracellular signal regulated kinase 1/2, protein kinase B and p38 mitogen activated protein kinase."
33435313
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"Increased expression and distribution of EGF, FGF, TGF-beta, VEGF, PI3K, MMP and Nrf2 and decreased expression and distribution of TNFalpha and NF-kappaB p65 were observed in diabetic wound treated with topical mangiferin."
32013660