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"Taken together, these data indicate that ICP0 can interact with and promote the proteasome dependent degradation of both USP7 and USP7 beta during HSV-1 infection.ICP0 belongs to the RING-finger class[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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"This hypothesis is supported by our finding that proteasome inhibition with MG132 abrogated USP7 inhibition‐induced downregulation of MDM2 and upregulation of p53 in SnCs."