IndraLab

Statements


Kinase-active CCND1 bound to CDK4 leads to the phosphorylation of RB1. 1 / 1
1 |

"The primary substrates of CDK4/6 and CDK2 in G1 progression are the members of the retinoblastoma protein family RB,p107 and p130 The activity of the RB proteins is modulated by sequential phosphorylation by CDK4/6cyclinD and CDK2cyclinE complexes"