IndraLab

Statements

NAMPT increases the amount of NOTCH1. 3 / 4
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"Considering that Notch1 acts as an oncogene and as a tumor suppressor in human cancer, it will be interesting to investigate whether visfatin also promotes Notch1 expression in other types of cancer, including skin cancer, hepatocellular carcinoma, and head and neck squamous cell carcinoma, in which Notch1 functions as a tumor suppressor."
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"At present, we do not know whether NF-kappaB p65 directly or indirectly mediates the induction of Notch1 expression by visfatin."
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"Here, we provide evidence for the regulation of Notch1 gene expression by visfatin and describe the role of the visfatin-Notch1 axis in breast cancer cells."
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