IndraLab

Statements

USP43 activates Neoplasm Metastasis. 9 / 9
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"This study reveals that USP43 promotes aerobic glycolysis and metastasis in BLCA by stabilizing c-Myc, thus providing a novel target for indirect inhibition of c-Myc."
38218970
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"In addition, studies have shown that USP43 mediates metastasis in breast and colon cancer [12, 59], but it has not been reported in ovarian cancer metastasis or recurrence, and it will be a direction for our investigation in the future.In conclusion, USP43 impaired cisplatin sensitivity by activating the Wnt/β-catenin signaling pathway via HDAC2 deubiquitylation, thereby promoting EOC progression."
38087046
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"In breast cancer, USP43 promotes invasion and metastasis through invadopodia formation."
38613804
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"In BLCA, USP43 promotes glycolysis and metastasis."
38613804
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"In vivo, USP43 knockdown led to reduced tumor growth and lung metastasis."
39922114
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"Overall, these findings suggest that USP43 promotes BLCA cell metastasis."
38218970
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"USP43 promotes glycolysis and metastasis in bladder cancer (BLCA)."
38613804
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"Moreover, USP43 may stimulate the metastasis of BLCA."
38613804
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"To further investigate if USP43 mediated the function of Ca 2.2 in metastasis in vivo, we transplanted luciferase-tagged MDA-MB-436 cells stably expressing Ca 2.2 shRNA and USP43 cDNA constructs into mice."
36137995