IndraLab

Statements

Rosuvastatin inhibits KCNH2. 4 / 4
1 | 3
reach
"Rosuvastatin blocks hERG current and prolongs cardiac repolarization."
22081364
reach
"Since chemical structure of rosuvastatin is similar to that of several IKr blockers (ibutilide and E-4031), the present study aimed to reveal the mechanism that underlies rosuvastatin induced hERG current reduction and to evaluate the possibility of cardiac toxicity."
30807184
reach
"The results showed that rosuvastatin reduced hERG currents by accelerating the inactivation and prolonged action potential duration (APD) in hiPSC-CMs."
30807184
ctd
No evidence text available
28551711