IndraLab

Statements

USP15 binds MAPK1. 10 / 10
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"Immunoprecipitation and deubiquitination assays were used to examine whether USP15 could bind to ERK2 and affect the deubiquitination of ERK2."
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"And USP15 can form a complex with ERK2 to regulate ubiquitination of ERK2."
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"USP15 can form a complex with ERK2."
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"Indeed, endogenous USP15 can form a complex with endogenous ERK2 in rat articular chondrocytes (Fig. xref a and Supplementary Fig.  xref a, b)."
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reach
"Immunoprecipitation and deubiquitination assays were used to examine whether USP15 could bind to ERK2 and affect the deubiquitination of ERK2."
33726807
reach
"And USP15 can form a complex with ERK2 to regulate ubiquitination of ERK2."
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sparser
"Since USP15 can interact with ERK2, we hypothesized that USP15 deubiquitinates ERK2."
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"Mechanistically, USP15 interacted with ERK2 and form a complex to govern the ubiquitination of ERK2."
37359559
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"These results indicated that although USP15 can bind to and deubiquitinate ERK2, USP15 was not resistant to degradation by the ERK2 ubiquitination hydrolase."
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"Co-immunocoprecipitation assays in our current studies showed that USP15 could bind to ERK2."
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