IndraLab

Statements


USP9X inhibits CFLAR. 4 / 4
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"WP1130 Enhances TRAIL Induced Apoptosis through USP9X Dependent miR-708-Mediated Downregulation of c-FLIP."

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"Interestingly, knockdown of USP9X markedly induced c-FLIP downregulation, upregulation of miR-708 expression and sensitivity to TRAIL."

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"Furthermore, ectopic expression of USP9X prevented c-FLIP downregulation and apoptosis upon combined treatment."

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"DGS promotes TRAIL-triggered apoptotic cell death via USP9X-dependent miR-708-regulated decrease of c-FLIP [36]."