IndraLab

Statements

Tat inhibits KCNH2. 8 / 8
| 7 1
reach
"As shown in Fig. 1 E of the representative recordings, compared with the control and inactivated HIV Tat protein (HIV Tat protein was inactivated by heating), HIV Tat protein (200 ng/ml) significantly[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
21820442
sparser
"Results showed that treatment of HIV Tat protein (200 ng/ml) for 24 h significantly increased ROS generation and the antioxidant tempol prevented HIV Tat induced hERG channel inhibition ( Figs."
21820442
reach
"HIV Tat protein inhibits hERG K+ channels : a potential mechanism of HIV infection induced LQTs."
21820442
reach
"Since HIV Tat protein had no the acute effect on hERG K + currents, but inhibited hERG currents after 24 h incubation, we speculated that HIV Tat protein might inhibit hERG K + currents through the in[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
21820442
reach
"Results showed that treatment of HIV Tat protein (200 ng/ml) for 24 h significantly increased ROS generation and the antioxidant tempol prevented HIV Tat induced hERG channel inhibition (Figs. 2 E and[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
21820442
reach
"Results were shown in Figs. 2 G and H. Although we found HIV Tat protein inhibited hERG K + channels but not Kv4.3 and Kv4.2 K + channels, we did not think it only specifically affected hERG K + chann[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
21820442
reach
"HIV Tat protein at 200 ng/ml concentration showed no acute effect on hERG currents, but HIV Tat protein (200 ng/ml) incubation for 24 h significantly inhibited hERG currents."
21820442
reach
"Therefore, we thought that the kinetics changes of hERG channels in HIV Tat incubated cells contributed negligibly to the HIV Tat induced decreases of hERG K + currents."
21820442