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"These data suggest that the interaction between OTUB2 and L3MBTL1 is constitutive rather than DNA damage dependent.Next, we investigated whether OTUB2 could deubiquitinate L3MBTL1 in vivo."

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"Therefore, we focused on L3MBTL1 and asked whether OTUB2 prevented RNF8 mediated ubiquitination of L3MBTL1.First, to confirm whether OTUB2 interacts with L3MBTL1, we performed a coimmunoprecipitation [MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"