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USP8 deubiquitinates DDX3X. 3 / 3
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"Consistent with the phenomenon that overexpression of USP8 led to the deubiquitination of DDX3X, USP8 deficiency resulted in increased ubiquitination of endogenous DDX3X compared with that in WT cells[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"These results suggested that USP8 promoted the deubiquitination of DDX3X to enhance the stability of DDX3X + SG."
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"The interaction between DDX3X and cGAS was impaired when DDX3X was ubiquitinated ( Figure S5 H), while the interaction was enhanced when DDX3X was deubiquitinated by USP8 ( Figure S5 I)."
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