IndraLab

Statements

OTUD1 inhibits immune response. 2 / 2
| 2
reach
"Additionally, OTUD1 and FGL1 depletion significantly restored TNFα-reduced anticancer immunity and prolonged the OS of mice stimulated with TNFα (Fig. 6C, D, S5D), consistent with the above in vitro findings."
37872170
reach
"For example, USP3 and CYLD were reported to negatively regulate type I IFN induction by targeting RIG-I ( Cui et al., 2014 ; Friedman et al., 2008 ); OTUD1 potently inhibits innate antiviral immunity [MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
32679077