IndraLab

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USP7 inhibits P5091. 2 / 2
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"USP7 was inhibited (P5091, Selleck #S7132, Selleck Chemicals, Houston, TX, USA) with doses ranging from 0.1 to 4 µM for 2–72 h. For measurement of growth rates, 100,000 cells were seeded in T-25 cell culture flasks and treated as indicated."
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"However, senescent p53 knockout cells were resistant to apoptosis and cell death caused by USP7 inhibition with P5091 (Figure 3a, b)."
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