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SRC activates KCNH2. 4 / 4
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"The hERG current was decreased by an EGFR inhibitor (AG556) and a broad-spectrum inhibitor of Src family tyrosine kinases (PP2) XREF_BIBR."
24587194
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"It is unknown whether this opposite regulatory effect of Kir2.1 channels by PTKs is due to different expression systems, cell types and/or experimental conditions.Both EGFR kinase and Src related kina[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
21570948
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"These results suggest that reduction of cardiac I hERG.tail by AG556 is likely mediated by EGFR kinase.The Src family kinase inhibitor PP2 was applied to determine whether Src family kinases modulate [MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
18617000
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"First, we show that tyrosine kinase inhibitor, PP1, and the selective Src inhibitory peptide, Src40-58, reduce the hERG current amplitude, without altering its voltage dependence or kinetics."
24587194