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BRCC3 inhibits TNF. 2 / 2

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"In addition, Real-time PCR analyses indicated that the ablation of BRCC3 reduced the expression of the NF-κB signaling down-stream genes including cIAP2, TNFα, and ICAM (Figure 4F)."

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"Moreover, alcohol-induced upregulation of TNF-α, IL-6, CXCL1, and CXCL2 mRNA expression was inhibited by BRCC3 ablation (Fig. 3C)."

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BRCC3 inhibits TNF. 2 / 2

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