IndraLab

Statements

POMC activates mutated USP48. 1 / 1

| 1

reach

"We provide evidence that Gli1 is at least in part responsible for the increased ACTH synthesis in USP48 mutant corticotroph cells, while we suspect that USP48-induced H2A deubiquitination dissociates it from DNA damage repair proteins and deregulates DNA repair."

31222332

INDRA sources:

Colored badges next to statement headings correspond to evidence counts from knowledge sources, as shown below. Badges to the left of the | separator correspond to curated knowledge base sources, and badges to the right of it correspond to machine reading systems.

IndraLab

Statements

POMC activates mutated USP48. 1 / 1

INDRA sources:

Databases

Reading