IndraLab

Statements



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"The roles of USP13 and the newly synthesized protein in liver inflammation, injury, and repair will be the future focuses."

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"We found that after a long-term HFHC/WTDF administration, dysfunctional USP13 in hepatocytes significantly promoted hepatic steatosis, liver inflammation, and hepatofibrosis."

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"Hepatocyte-specific loss of the Usp13 disrupts liver metabolic homeostasis, followed by glycometabolic disorder, lipid deposition, increased inflammation, and markedly promotes NASH development."

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"In collagen-mediated arthritis (CIA) mice, USP13 attenuated synovial hyperplasia, cartilage damage and inflammation and bone loss (102)."