IndraLab

Statements


Cas9 inhibits USP48. 2 / 2
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sparser
"Further confirming that the synthetic rescue was indeed dependent on USP48, when we subjected USP48 to short-hairpin RNA (shRNA) depletion (Supplementary Fig.  xref ) or carried out USP48 gene inactivation by CRISPR-Cas9 editing by using a different single guide (sg)RNA targeting a different exon (Supplementary Fig.  xref ) in Δ FANCC cells, we observed similar results."

reach
"Construction of stable cell lines and CRISPR/Cas9-mediated USP48 knockout in stable cells and neurons.."