IndraLab

Statements

BAP1 activates Neoplasm Invasiveness. 13 / 13
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"Consistently, silence of BAP1 or KLF5 expression significantly decreased the invasion of HCC1937 cells in transwell matrigel invasion assays (XREF_FIG)."
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"BRCA1 associated protein 1 deficiency in lung adenocarcinoma predicts poor outcome and increased tumor invasion."
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"Although BAP1 is a tumor suppressor when overexpressed, the knockdown of BAP1 in wild-type UM cells also suppressed cell growth and invasiveness ( Matatall et al., 2013 )."
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"This suggests BAP1 may cooperate with other genes to mediate cell invasion and metastasis.BAP1 was recently identified as a transcriptional coregulator that binds indirectly to promoters close to tran[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"Germline or somatic mutations and deletions of BAP1 have been identified in various tumor types, and downregulation or inactivation of BAP1 could accelerate tumor onset, invasion, recurrence, and metastases ."
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"BAP1 and BCL9L, as oncogenes, promote the growth, invasion and lung metastasis of breast cancer by interacting with β-catenin and Pygopus (39-41)."
34988168
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"BAP1 may inhibit the progression of LAC by attenuating tumor invasiveness, a function that was supported by the findings of the Transwell assay."
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"Downregulation of BAP1 promotes proliferation, cell cycle progression, and invasion of ICC in vitro."
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"Germline or somatic mutations and copy number alterations have been identified in several cancers and inactivation of BAP1 accelerates invasion, recurrence and metastases."
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"The simultaneous occurrence of SF3B1 mutations and BAP1 deficiency in Mel202 cells reduced their invasion capacity in the zebrafish xenograft model."
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"We also report a positive correlation between BAP1 and patient outcome and provide evidence that BAP1 overexpression promotes migration and invasion of adenocarcinoma."
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"Taken together, these data revealed that downregulation of BAP1 promotes proliferation, G1 to S cell cycle progression, and invasion of ICC in vitro."
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"BAP1 and KLF5 promote breast cancer migration, invasion and metastasis may not through p27; however, KLF5 is a transcription factor regulating numerous downstream target genes, such as FGF-BP and mPGES1."
26419610