IndraLab

Statements

SCN8A inhibits Heart Rate. 3 / 3
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"MED infusion alone increased SAP maximally by 24.9%, MAP by 34.7% and a-vO2 diff by 222.5%, and reduced HR by 32.3%, but these changes were significantly attenuated by MK-467."
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"However, the MED trial significantly attenuated the exercise induced increase in HR."
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"The I max estimates indicate that MED and DEX reduce the HR by 31%, while DET reduces HR by approximately 51%."
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