IndraLab

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Doxycycline activates USP39. 3 / 3
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"Doxycycline was administered to induce USP39 slicing by oral gavage."
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"In addition, we conducted transwell assays to detect cell movement and the results revealed that doxycycline-induced USP39 knockdown drastically suppressed A549 and H1299 cell migration (Fig. S2G, H)."
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"USP39 downregulation induced by doxycycline dramatically inhibited the growth of A549 and H1299 cells, as demonstrated by MTT and colony formation assays (Fig. S2C-F)."
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