IndraLab

Statements

OLR1 activates TRPV1. 3 / 3
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"Zhao and colleagues found that oxLDL-stimulated bone marrow-derived macrophages showed an increased level of TRPV1 expression and oxLDL activated TRPV1 which led to intracellular Ca 2+ -transients that were abolished by superfusion with the TRPV1 antagonist capsazepine."
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"OxLDL activates TRPV1 in BMDMs and initiates lipid accumulation induced by Ca2+ influx ( xref )."
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"In addition, oxLDL activated TRPV1 and elicited calcium (Ca 2+ ) influx, which were abrogated by the pharmacological TRPV1 antagonist capsazepine."
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