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JOSD2 activates Hypertrophy. 2 / 2

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"By regulating SERCA2a, JOSD2 deficiency impairs calcium handling and promotes hypertrophy in primary cardiomyocytes."

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"Josd2 gene knockout aggravated cardiac dysfunction and hypertrophy in mice, whereas cardiac overexpression of JOSD2 mediated by the AAV9 vector prevented angiotensin II-induced cardiac hypertrophy."

39195964

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JOSD2 activates Hypertrophy. 2 / 2

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