IndraLab

Statements


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"Brazilin suppressed the IL1beta mediated upregulation of OA markers and the induction of NFKB1 and p50 in chondrocytes."

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"Previous studies have reported that Brazilin inhibits NFkB/p50 signaling in cartilage and chondrocytes obtained from osteoarthritis patients (Weinmann et al., 2018)."

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"Additionally, it has been reported that Brazilin decreased ERK and NFkB signaling in RANKL-stimulated RAW264.7 cells (Kim et al., 2015)."

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"Brazilin was able to suppress the IL-1β-induced upregulation of osteoarthritic (OA) markers and the activation of NFKB1/p50 in chondrocytes, suggesting a protective effect against OA progression."

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"Brazilin suppressed the IL1beta mediated upregulation of OA markers and the induction of NFKB1 and p50 in chondrocytes."